| Date | Location | Result | |
| 02/25/00 | Penn State Behrend | Frostburg State University 69, Penn State Altoona Cougars 63 | Box score |
| 02/23/00 | Adler Athletic Complex | Penn State Altoona Cougars 82, Univerisity of Pitt-Greensburg 51 | Box score |
| 02/16/00 | Adler Athletic Complex | Penn State Altoona Cougars 79, Lake Erie College 40 | Box score |
| 02/11/00 | University of Pitt-Bradford | Penn State Altoona Cougars 72, University of Pitt-Bradford 48 | Box score |
| 02/09/00 | Adler Athletic Complex | Penn State Altoona Cougars 66, LaRoche College 54 | Box score |
| 02/07/00 | Adler Athletic Complex | Penn State Altoona Cougars 54, Bethany College 53 | Box score |
| 02/05/00 | Adler Athletic Complex | Frostburg State University 64, Penn State Altoona Cougars 55 | Box score |
| 02/02/00 | Penn State Erie | Penn State Erie 68, Penn State Altoona Cougars 48 | Box score |
| 01/31/00 | Lycoming College | Lycoming College 67, Penn State Altoona Cougars 49 | Box score |
| 01/29/00 | University of Pitt-Greensburg | Penn State Altoona Cougars 61, Univerisity of Pitt-Greensburg 49 | Box score |
| 01/27/00 | Adler Athletic Complex | Juniata College 79, Penn State Altoona Cougars 78 | Box score |
| 01/24/00 | Adler Athletic Complex | Penn State Altoona Cougars 67, Dickinson 52 | Box score |
| 01/22/00 | Lake Erie College | Penn State Altoona Cougars 69, Lake Erie College 42 | Box score |
| 01/19/00 | Adler Athletic Complex | Penn State Altoona Cougars 61, University of Pitt-Bradford 47 | Box score |
| 01/18/00 | Adler Athletic Complex | Mount Aloysius 59, Penn State Altoona Cougars 49 | Box score |
| 01/15/00 | LaRoche College | Penn State Altoona Cougars 51, LaRoche College 36 | Box score |
| 01/12/00 | Forstburg State University | Frostburg State University 57, Penn State Altoona Cougars 45 | Box score |
| 01/10/00 | Carlow College | Carlow College 68, Penn State Altoona Cougars 46 | Box score |
| 01/08/00 | Adler Athletic Complex | Penn State Altoona Cougars 55, Thiel College 44 | Box score |
| 12/11/99 | Adler Athletic Complex | Penn State Erie 57, Penn State Altoona Cougars 45 | Box score |
| 12/08/99 | Adler Athletic Complex | Penn State Altoona Cougars 67, Univerisity of Pitt-Greensburg 37 | Box score |
| 12/06/99 | Holy Family College | Holy Family College 85, Penn State Altoona Cougars 46 | Box score |
| 11/30/99 | Thiel College | Thiel College 66, Penn State Altoona Cougars 59 | Box score |
| 11/20/99 | Messiah College | Penn State Altoona Cougars 74, Eastern Mennonite University 54 | Box score |
| 11/19/99 | Messiah College | Alvernia College 61, Penn State Altoona Cougars 58 | Box score |